TRIM5alpha
Pathogen resistance (retroviruses)
Coding,
SNP
Cercopithecidae
Old World monkeys - (family)
Intraspecific
Candidate Gene
Newman RM; Hall L; Connole M ; et al. (2006)
Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha.
GP00001135
TRIM5
Q9C035
Physiology
several a.a. substitutions with retrovirus-specific activities; under balancing selection in several species
Cercopithecidae
Old World monkeys - (family)
Cercopithecidae
Old World monkeys - (family)
TRIM5alpha
Cercopithecidae
Old World monkeys - (family)
Published - Accepted by Curator
TRIM5alpha-CypA chimeric gene
Pathogen resistance (retroviruses)
Other,
Insertion
Aotus
night monkeys - (genus)
Intergeneric or Higher
Candidate Gene
Sayah DM; Sokolskaja E; Berthoux L ; et al. (2004)
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1.
1 Additional References
GP00001136
TRIM5
Q9C035
Physiology
LINE-mediated retrotransposition of the CyclophilinA gene between exons 7 and 8 of TRIM5alpha
Platyrrhini
New World monkeys - (parvorder)
Aotus
night monkeys - (genus)
TRIM5alpha-CypA chimeric gene
Aotus
night monkeys - (genus)
Published - Accepted by Curator
TRIM5alpha-CypA chimeric gene
Pathogen resistance (retroviruses)
Other,
Insertion
Macaca
macaques - (genus)
Intergeneric or Higher
Candidate Gene
Stoye JP; Yap MW (2008)
Chance favors a prepared genome.
GP00001137
TRIM5
Q9C035
Physiology
LINE-mediated retrotransposition of the CyclophilinA gene into 3'UTR (exon 8) of TRIM5alpha
Cercopithecidae
Old World monkeys - (family)
Macaca
macaques - (genus)
TRIM5alpha-CypA chimeric gene
Macaca
macaques - (genus)
Published - Accepted by Curator